606 research outputs found

    ENTRAP and its potential interaction with European networks

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    AbstractENTRAP comprises a pan-European cooperation of leading scientific institutions and regulatory bodies in the field of nuclear-waste characterization and its quality assurance for the safe disposal of radioactive waste. Here, the scope of this cooperation is presented and explained and links or interfaces for a potential collaboration with partners fulfilling tasks of IDG-TP are pursued

    Correlations and Renormalization in Lattice Gases

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    A complete formulation is given of an exact kinetic theory for lattice gases. This kinetic theory makes possible the calculation of corrections to the usual Boltzmann / Chapman-Enskog analysis of lattice gases due to the buildup of correlations. It is shown that renormalized transport coefficients can be calculated perturbatively by summing terms in an infinite series. A diagrammatic notation for the terms in this series is given, in analogy with the diagrammatic expansions of continuum kinetic theory and quantum field theory. A closed-form expression for the coefficients associated with the vertices of these diagrams is given. This method is applied to several standard lattice gases, and the results are shown to correctly predict experimentally observed deviations from the Boltzmann analysis.Comment: 94 pages, pure LaTeX including all figure

    The tomato cytochrome P450 CYP712G1 catalyzes the double oxidation of orobanchol <i>en route</i> to the rhizosphere signaling strigolactone, solanacol

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    Strigolactones (SLs) are rhizosphere signalling molecules and phytohormones. The biosynthetic pathway of SLs in tomato has been partially elucidated, but the structural diversity in tomato SLs predicts that additional biosynthetic steps are required. Here, root RNA-seq data and co-expression analysis were used for SL biosynthetic gene discovery. This strategy resulted in a candidate gene list containing several cytochrome P450s. Heterologous expression in Nicotiana benthamiana and yeast showed that one of these, CYP712G1, can catalyse the double oxidation of orobanchol, resulting in the formation of three didehydro-orobanchol (DDH) isomers. Virus-induced gene silencing and heterologous expression in yeast showed that one of these DDH isomers is converted to solanacol, one of the most abundant SLs in tomato root exudate. Protein modelling and substrate docking analysis suggest that hydroxy-orbanchol is the likely intermediate in the conversion from orobanchol to the DDH isomers. Phylogenetic analysis demonstrated the occurrence of CYP712G1 homologues in the Eudicots only, which fits with the reports on DDH isomers in that clade. Protein modelling and orobanchol docking of the putative tobacco CYP712G1 homologue suggest that it can convert orobanchol to similar DDH isomers as tomato

    Heritability and reliability of automatically segmented human hippocampal formation subregions

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    The human hippocampal formation can be divided into a set of cytoarchitecturally and functionally distinct subregions, involved in different aspects of memory formation. Neuroanatomical disruptions within these subregions are associated with several debilitating brain disorders including Alzheimer's disease, major depression, schizophrenia, and bipolar disorder. Multi-center brain imaging consortia, such as the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) consortium, are interested in studying disease effects on these subregions, and in the genetic factors that affect them. For large-scale studies, automated extraction and subsequent genomic association studies of these hippocampal subregion measures may provide additional insight. Here, we evaluated the test-retest reliability and transplatform reliability (1.5 T versus 3 T) of the subregion segmentation module in the FreeSurfer software package using three independent cohorts of healthy adults, one young (Queensland Twins Imaging Study, N=39), another elderly (Alzheimer's Disease Neuroimaging Initiative, ADNI-2, N=163) and another mixed cohort of healthy and depressed participants (Max Planck Institute, MPIP, N=598). We also investigated agreement between the most recent version of this algorithm (v6.0) and an older version (v5.3), again using the ADNI-2 and MPIP cohorts in addition to a sample from the Netherlands Study for Depression and Anxiety (NESDA) (N=221). Finally, we estimated the heritability (h(2)) of the segmented subregion volumes using the full sample of young, healthy QTIM twins (N=728). Test-retest reliability was high for all twelve subregions in the 3 T ADNI-2 sample (intraclass correlation coefficient (ICC)=0.70-0.97) and moderate-to-high in the 4 TQTIM sample (ICC=0.5-0.89). Transplatform reliability was strong for eleven of the twelve subregions (ICC=0.66-0.96); however, the hippocampal fissure was not consistently reconstructed across 1.5 T and 3 T field strengths (ICC=0.47-0.57). Between-version agreement was moderate for the hippocampal tail, subiculum and presubiculum (ICC=0.78-0.84; Dice Similarity Coefficient (DSC)=0.55-0.70), and poor for all other subregions (ICC=0.34-0.81; DSC=0.28-0.51). All hippocampal subregion volumes were highly heritable (h(2)=0.67-0.91). Our findings indicate that eleven of the twelve human hippocampal subregions segmented using FreeSurfer version 6.0 may serve as reliable and informative quantitative phenotypes for future multi-site imaging genetics initiatives such as those of the ENIGMA consortium. (C) 2016 The Authors. Published by Elsevier Inc

    Transient processing and analysis using AMPEL: alert management, photometry, and evaluation of light curves

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    Context. Both multi-messenger astronomy and new high-throughput wide-field surveys require flexible tools for the selection and analysis of astrophysical transients. Aims. Here we introduce the alert management, photometry, and evaluation of light curves (AMPEL) system, an analysis framework designed for high-throughput surveys and suited for streamed data. AMPEL combines the functionality of an alert broker with a generic framework capable of hosting user-contributed code; it encourages provenance and keeps track of the varying information states that a transient displays. The latter concept includes information gathered over time and data policies such as access or calibration levels. Methods. We describe a novel ongoing real-time multi-messenger analysis using AMPEL to combine IceCube neutrino data with the alert streams of the Zwicky Transient Facility (ZTF). We also reprocess the first four months of ZTF public alerts, and compare the yields of more than 200 different transient selection functions to quantify efficiencies for selecting Type Ia supernovae that were reported to the Transient Name Server (TNS). Results. We highlight three channels suitable for (1) the collection of a complete sample of extragalactic transients, (2) immediate follow-up of nearby transients, and (3) follow-up campaigns targeting young, extragalactic transients. We confirm ZTF completeness in that all TNS supernovae positioned on active CCD regions were detected. Conclusions. AMPEL can assist in filtering transients in real time, running alert reaction simulations, the reprocessing of full datasets as well as in the final scientific analysis of transient data. This is made possible by a novel way of capturing transient information through sequences of evolving states, and interfaces that allow new code to be natively applied to a full stream of alerts. This text also introduces a method by which users can design their own channels for inclusion in the AMPEL live instance that parses the ZTF stream and the real-time submission of high-quality extragalactic supernova candidates to the TNS

    Discovery of a Fast Iron Low-ionization Outflow in the Early Evolution of the Nearby Tidal Disruption Event AT2019qiz

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    We report the results of UV and optical photometric and spectroscopic analysis on the tidal disruption event (TDE) AT2019qiz. Our follow-up observations started shortly after (≲\lesssim10 days) its optical light begin to rise and lasted for a period of six months. Our late-time host-dominated spectrum indicates that the host galaxy likely harbours a weak AGN. The initial HST spectrum of AT2019qiz exhibits a iron and low-ionization broad absorption line (FeLoBAL) system that is seen for the first time in a TDE. This spectrum also bears a striking resemblance to that of Gaia16apd, a superluminous supernova. Our observations provide insights into the outflow properties in TDEs and show evidence for a connection between TDEs and engine-powered supernovae at early phase, as originally suggested in Metzger & Stone (2016). In a time frame of 50 days, the UV spectra of AT2019qiz started to resemble previous TDEs with only high-ionization BALs. The change in UV spectral signatures is accompanied by a decrease in the outflow velocity, which began at 15,00015,000 km s−1^{-1} and decelerated to ∼10,000\sim10,000 km s−1^{-1}. A similar evolution in the Hα\alpha emission line width further supports the speculation that the broad Balmer emission lines are formed in TDE outflows. In addition, we detect narrow absorption features on top of the FeLoBAL signatures in the early HST UV spectrum of AT2019qiz. The measured HI column density corresponds to a Lyman-limit system whereas the metal absorption lines, such as NV, CIV, FeII, and MgII, are likely probing the circumnuclear gas and interstellar medium in the host galaxy.Comment: 24 pages, 13 figures, 3 tables. Submitted to ApJ on Nov 03 202
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